![]() ![]() ![]() Bleeker-Rovers CP, Vos FJ, de Kleijn EMHA, et al. Fever of unknown origin (FUO): which are the factors influencing the final diagnosis? A 2005-2015 systematic review. Subsequent authors have suggested quantitative criteria (i.e., diagnosis uncertain after 1 week or 3 days of investigation) with a qualitative requirement, namely that the fever remains undiagnosed after a minimal diagnostic work-up has been performed. Fusco FM, Pisapia R, Nardiello S, et al. Fever of unknown origin - reexamined and redefined. 1961 Feb 40:1-30.Ī revised frequency/duration of evaluation has been proposed: "at least 3 outpatient visits or 3 days in hospital". ![]() Fever of unexplained origin: report on 100 cases. Fever of unknown origin (FUO) has been defined as a temperature >100.9☏ (>38.3☌) on several occasions lasting for more than 3 weeks, with no obvious source despite evaluation of at least 1 week in hospital. ![]()
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